Studi In-Silico Senyawa Luteolin sebagai Kandidat Obat Antikanker Payudara
Abstract
Full Text:
PDFReferences
Adriani. 2018. Prediksi Senyawa Bioaktif Dari Tanaman Sanrego (Lunasia amara Blanco) Sebagai Inhibitor Enzim Siklooksigenase-2 (COX-2) Melalui Pendekatan Molecular Docking. Jurnal Ilmiah Pena, 1(1), 6-11.
Berk, V.L.C., Landi, E., Walma, T., Vuister, G.W., Dente, L., Hendriks, W.J. 2007. An allosteric intramolecular PDZ-PDZ interaction modulates PTP-BL PDZ2 binding specificity. Biochemistry, 46, 13629-13637.
Chimed, T., Sandagdorj, T., Znaor, A., Laversanne, M., Tseveen, B., Genden, P., & Bray, F. (2017). Cancer incidence and cancer control in Mongolia: Results from the National Cancer Registry 2008–12. International Journal of Cancer, 140(2), 302–309.
Cook, M.T., Mafuvadze, B., Besch-Williford, C., Ellersieck, M.R., & Hyder, S.M. 2016. Luteolin suppresses development of medroxyprogesterone acetate-accelerate 7,12- dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats. Oncol. Rep, 35 (2), 825–832.
Fauziah, A., Fatharani, A., Nurawaliah, C. M., Rivianto, F. A., Sakina, I. V., Rahmawati, M., & Nurfadhila, L. 2023. Molecular Docking Of Compound With Potential As Anti-breast Cancer: Literature Review. Journal of Pharmaceutical and Sciences, 6(2), 416–427.
Gunasekaran, Ramakrishnan and Balaram, 1996. Disallowed Ramachandran Conformations of Amino Acid Residues in Protein Structures. Journal of Molecular Biology, 264, 191 – 198.
Imran, M., Rauf, A., Abu-Izneid, T., Nadeem, M., Shariati, M.A., Khan, I.A., Imran, A., Orhan, I.E., Rizwan, M., Atif, M., Gondal, T.A., Mubarak, M.S. 2019. Luteolin, a flavonoid, as an anticancer agent: A review. Biomedicine & Pharmacotherapy, 112(2019), 108612.
Lipinski, C.A. 2004. Lead and drug-like compounds: The rule-of-five revolution. Drug Discovery Today: Technologies, 1(4), 337–341.
Marthasari, N.K.P., Ariana, P.A., Pratama, A.A., Aryawan, K.Y., & Heri, M. 2022. Sadari: Upaya Mencegah Kanker Payudara Pada Usia Remaja. Jurnal Abdi Masyarakat, 2(2), 79-83.
Saudale, F.Z. 2020. Pemodelan Homologi Komparatif Struktur 3D Protein Dalam Desain dan Pengembangan Obat. Al-Kimia, 8(1), 93-103.
Selvendiran, K., Koga, H., Ueno, T., Yoshida, T., Maeyama, M., Torimura, T., Yano, H., Kojiro, M., & Sata, M. 2006. Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatomacells: an implication for the antitumor potential of flavonoids. Cancer Res, 66, 4826–4834.
Shi, Y. (2014). A glimpse of structural biology through X-ray crystallography. Cell, 159(5), 995-1014.
Slabinski, L., Jaroszewski, L., Rodrigues, A. P., Rychlewski, L., Wilson, I. A., Lesley, S. A., & Godzik, A. (2007). The challenge of protein structure determination—lessons from structural genomics. Protein Science, 16(11), 2472–2482.
World Health Organization. 2020. Cancer Indonesia 2020 country profile. Diunduh dari https://www.who.int/publications/m/item/cancer-idn-2020, pada 29 Oktober 2023.
World Health Organization. 2023. Cancer Overview. Diunduh dari https://www.who.int/health-topics/cancer#tab=tab_1, pada 28 Oktober 2023.
Refbacks
- There are currently no refbacks.
Faculty of Mathematics and Sciences Universitas Indraprasta PGRI Address: Jl. Raya Tengah No. 80, Kel. Gedong, Kec. Pasar Rebo, Jakarta Timur 13760 , Jakarta, Indonesia. |
![]() Prosiding Seminar Nasional Sains 2020 is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. |